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Accession Type:
Network
AMPAR_CaMKII_
strong_coupling
Shared_Object_
AMPAR_CaMKII_
strong_coupling
CaMKII
 Molecule
 Enzyme
 Reaction
CaM
PP1
AMPAR_memb
PP2B
PKA
AC
PP1_PSD
AMPAR

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Parameters for CaMKII (Pathway Number 272)

Pathway Layout

Pathway Basic Parameters

Pathway NameCaMKII
Pathway Entry Number 272
Accession Number 64
Accession Name AMPAR_CaMKII_strong_coupling
Species General Mammalian
Tissue Neuronal
CellCompartmentSynaptic Spine, Postsynaptic Density
Related Pathways 13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 282, 322, 339, 357
Notes Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.

Statistics

8
4
2

Conversion format

This pathway is part of accession 64 and is completely specified in the file acc64.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc64.g   
MATLAB format    acc64.m   
SBML format    acc64.xml   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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