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Accession Type:
Network
Synaptic_
Network
Shared_Object_
Synaptic_
Network
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
Sos
PLC_g
CaMKII
CaM
PP1
PP2B
PKA
AC
 Molecule
 Enzyme
 Reaction
CaRegulation

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Parameters for AC (Pathway Number 85)

Pathway Layout

Pathway Basic Parameters

Pathway NameAC
Pathway Entry Number 85
Accession Number 16
Accession Name Synaptic_Network
Species Generic mammalian
Tissue Neuronal
CellCompartmentSynapse
Related Pathways 18, 31, 136, 197, 221, 241, 251, 269, 278, 289, 327, 344, 362
Notes The adenylyl cyclase module currently represents only two isoforms: AC1 and AC2. There are at least 8 forms of AC known: Pieroni et al 1993 Curr Op Neurobiol 3:345-351. AC1 is stimulated by CaM, and AC2 by phosphorylation by PKC, in addition to the usual Gs stimulation. A more recent thorough review is Defer et al 2000 Am J Physiol Renal Physiol 279:F400-F416 This model does not incorporate effects such as GAP activity of the cyclases.

Statistics

13
9
7

Conversion format

This pathway is part of accession 16 and is completely specified in the file acc16.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc16.g   
GENESIS Format (Annotated version)    Anno_acc16.g   


Pathway Detail   Molecule List   Enzyme List   Reaction List  


Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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