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Molecule Parameter List for aTRKb

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*aTRKb* participated as	Molecule	Sum total of	Input	Product	Ligand/Activator	Modifier
No. of occurrences	1	0	0	1	1	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
syn_prot_ composite	109	Pathway	BDNF_g, S6K_g, CaMKIII_g, prot_g
This model was used to generate fig 5 D to k, fig 6 in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.

aTRKb acting as a Molecule in syn_prot_composite Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)
aTRKb	syn_prot_ composite Accession No. : 109	BDNF_g Pathway No. : 1143	0

aTRKb acting as prd in syn_prot_composite Network

Accession Name

Pathway Name

Product

Input

Ligand

Inhibit

tau

Modifier

Addition_parameter

syn_prot_composite
Accession No: 109

BDNF_g
Pathway No:1143

aTRKb

TRKb

BDNF

0.0001
(uM)

70
(s)

aS6K
aS6K

Amod : 0
Nmod : 2
Kmod : 0.53

Gain :0.82

Baseline :0

aTRKb acting as ligant in syn_prot_composite Network

Accession Name

Pathway Name

Product

Input

Ligand

Inhibit

tau

Modifier

Addition_parameter

syn_prot_composite
Accession No: 109

S6K_g
Pathway No:1144

aS6K

S6K

2 * aTRKb

0.92
(uM)

507
(s)

Ca
Ca
Ca
Ca

Amod : 113
Nmod : 4
Kmod : 0.434

Gain :0.45

Baseline :0

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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