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Molecule Parameter List for aS6K

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
aS6K participated asMoleculeSum total ofInputProductLigand/ActivatorModifier
No. of occurrences100112

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • syn_prot_
    composite
    		• 109Pathway
    BDNF_g,  S6K_g,  CaMKIII_g,  
    prot_g 
    This model was used to generate fig 5 D to k, fig 6 in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.

    aS6K acting as a Molecule in      syn_prot_composite Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    aS6K
  • syn_prot_
    composite
    Accession No. : 109
    		• S6K_g
    Pathway No. : 1144    		0

    aS6K acting as prd in  syn_prot_composite Network
    Accession NamePathway NameProductInputLigandInhibitKAtauModifierAddition_parameter
    syn_prot_composite
    Accession No: 109    		S6K_g
    Pathway No:1144    		aS6KS6K2 * aTRKb00.92
    (uM)    		507
    (s)    		Ca
    Ca
    Ca
    Ca

    Amod : 113
    Nmod : 4
    Kmod : 0.434
    Gain :0.45
    Baseline :0

    aS6K acting as ligant in  syn_prot_composite Network
    Accession NamePathway NameProductInputLigandInhibitKAtauModifierAddition_parameter
    syn_prot_composite
    Accession No: 109    		prot_g
    Pathway No:1146    		proteinAminoAcidsaS6K020
    (uM)    		157.3644
    (s)    		aCaMKIII

    Amod : 0.0149
    Nmod : 1
    Kmod : 0.0013
    Gain :0.0012
    Baseline :0

    aS6K acting as Modifier in  syn_prot_composite Network
    Accession NamePathway NameProductInputLigandInhibitKAtauModifierAddition_parameter
    syn_prot_composite
    Accession No: 109    		BDNF_g
    Pathway No:1143    		aTRKbTRKbBDNF00.0001
    (uM)    		70
    (s)    		aS6K
    aS6K

    Amod : 0
    Nmod : 2
    Kmod : 0.53
    Gain :0.82
    Baseline :0
    syn_prot_composite
    Accession No: 109    		CaMKIII_g
    Pathway No:1145    		aCaMKIIICaMKIII4 * Ca00.273
    (uM)    		4.69
    (s)
    Amod : 0.0005
    Nmod : 2
    Kmod : 0.169
    Baseline :0.0001


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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