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Molecule Parameter List for nNOS.OH.Arg | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | | NOS_Iwanaga | 11 | Pathway |
NOS | | This model is based on Iwanaga T et al. Biochemistry (1999) 38(50):16629-35.The model features the catalytic activity of neuronal Nitric Oxide Synthase expressed in Escherichia coli in a four step reaction mechanism. The rates found in the model are used directly from their paper and have been determined from experiments performed at 25 C. |
nNOS.OH.Arg acting as a Molecule in NOS_Iwanaga Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | nNOS.OH.Arg | NOS_Iwanaga
Accession No. : 11 | NOS
Pathway No. : 65 | 0 | 0.0016667 | No | | This is the intermediate formed during the catalytic activity of NOS in synthesising NO, N-hydroxy arginine. |
nNOS.OH.Arg acting as a Substrate in a reaction in NOS_Iwanaga Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| | Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | 1 | k3 | NOS_Iwanaga
Accession No. : 11 | NOS
Pathway No. : 65 | 19
(s^-1) | 0
(s^-1) | - | - | Substrate
nNOS.OH.Arg
Product
nNOS.Cit+NO
| | | Rate from Biochem., 1999, 38(50), 16629-16635. Obtained from rapid queching expts at 25 C >>>>>> 19 +/- 3.0 | | 2 | k2 | NOS_Iwanaga
Accession No. : 11 | NOS
Pathway No. : 65 | 4.4
(s^-1) | 0
(s^-1) | - | - | Substrate
nNOS.OH.Arg
Product
OH.Arg
| | | Rates from Biochem., 1999, 38(50), 16629-16635. obtained from rapid quenching expts at 25 C.... >>>>>> 4.4 +/- 0.5 |
nNOS.OH.Arg acting as a Product in a reaction in NOS_Iwanaga Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | k1 | NOS_Iwanaga
Accession No. : 11 | NOS
Pathway No. : 65 | 25
(s^-1) | 0
(s^-1) | - | - | Substrate
nNOS.arg
Product
nNOS.OH.Arg
| | Rates from Iwanaga et al., Biochem, 1999;38(50):16629-16635. Obtained from rapid quenching expts at 25 C. >>>>>> 25 +/- 2.0 |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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