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Molecule Parameter List for aS6K

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
aS6K participated asMoleculeSum total ofInputProductLigand/ActivatorModifier
No. of occurrences100102

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
syn_CaMKIII114Pathway
BDNF_g,  S6K_g,  CaMKIII_g 
This model was used to generate Fig 3 supp A to F in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.

aS6K acting as a Molecule in  syn_CaMKIII Network
NameAccession NamePathway NameInitial Conc.
(uM)
aS6Ksyn_CaMKIII
Accession No. : 114		S6K_g
Pathway No. : 1158		0

aS6K acting as prd in  syn_CaMKIII Network
Accession NamePathway NameProductInputLigandInhibitKAtauModifierAddition_parameter
syn_CaMKIII
Accession No: 114		S6K_g
Pathway No:1158		aS6KS6K2 * aTRKb00.92
(uM)		507
(s)		Ca
Ca
Ca
Ca

Amod : 113
Nmod : 4
Kmod : 0.434
Gain :0.45
Baseline :0

aS6K acting as Modifier in  syn_CaMKIII Network
Accession NamePathway NameProductInputLigandInhibitKAtauModifierAddition_parameter
syn_CaMKIII
Accession No: 114		BDNF_g
Pathway No:1157		aTRKbTRKbBDNF00.0001
(uM)		70
(s)		aS6K
aS6K

Amod : 0
Nmod : 2
Kmod : 0.53
Gain :0.82
Baseline :0
syn_CaMKIII
Accession No: 114		CaMKIII_g
Pathway No:1159		aCaMKIIICaMKIII4 * Ca00.2728
(uM)		4.6899
(s)
Amod : 0.0005
Nmod : 2
Kmod : 0.1692
Baseline :0.0001


Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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