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Molecule Parameter List for FeIII_a | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | Stuehr_NOS | 12 | Pathway | NOS | This is a model of neuronal Nitric Oxide Synthase expressed in Escherichia coli based on Santolini J. et al. J Biol Chem. (2001) 276(2):1233-43. The rates have been converted by 2x for every 10 degrees C. The original temperature was 10 degree C, cell temperature is assumed 30 degree C, so the conversion factor is 4. |
FeIII_a acting as a Molecule in Stuehr_NOS Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | FeIII_a | Stuehr_NOS Accession No. : 12 | NOS Pathway No. : 66 | 0 | 0.0016667 | No | |
FeIII_a acting as a Substrate in a reaction in Stuehr_NOS Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | k4 | Stuehr_NOS Accession No. : 12 | NOS Pathway No. : 66 | 10.4 (s^-1) | 0 (s^-1) | - | - | Substrate FeIII_a
Product FeII_a
| rates from Stuehr et al., 2001, JBC, 276(2):1233-1243 rates increased by 2X for every 10 C rise to get it to the cell temp.. (thru personal correspondence) kf -- 10.4 |
FeIII_a acting as a Product in a reaction in Stuehr_NOS Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | k3 | Stuehr_NOS Accession No. : 12 | NOS Pathway No. : 66 | 104 (s^-1) | 0 (s^-1) | - | - | Substrate FeII-O2
Product FeIII_a
| Rates from Stuehr et al., 2001, JBC, 276(2):1233-1243 rates increased by 2X for every 10 C rise, to get it to the cell temp.. (thru personal correspondence) kf -- 104 |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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