| Name | sGC_Stone_Marletta |
| Accession Type | Pathway |
| Transcriber | Sudhir Sivakumaran, NCBS |
| Developer | Stone and Marletta, 1996. |
| Entry Date (YYYY-MM-DD) | 2001-12-12 00:00:00 |
| Species | Bovine |
| Tissue | Lungs |
| Cell Compartment | Cytosol |
| Source | Stone JR, Marletta MA. Biochemistry (1996) 35(4):1093-9. ( peer-reviewed publication ) |
| Methodology | Quantitative match to experiments |
| Model Implementation | Mathematically equivalent |
| Model Validation | Replicates orginal data |
| Notes | This features the two step binding of NO to soluble Guanylyl Cyclase as proposed by Stone JR, Marletta MA. Biochemistry (1996) 35(4):1093-9. There is a fast step binding scheme and a slow step binding scheme. The difference lies in the binding of a NO to a non-heme site on sGC, which may not necessarily be the same site of binding during the initial binding. The rates have been directly used from their models |
