 | Kuroda_GC | |
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Accession information for Kuroda_GC (Accession Number 18)
Reaction Scheme
Accession Basic Parameters
| Name | Kuroda_GC |
| Accession Type | Pathway |
| Transcriber | Sudhir Sivakumaran, NCBS |
| Developer | Shinya Kuroda, Nicolas Schweighofer and Mitsuo Kawato. |
| Entry Date (YYYY-MM-DD) | 2001-12-24 00:00:00 |
| Species | Generic mammalian |
| Tissue | Neuronal |
| Cell Compartment | Synapse |
| Source | Kuroda S. et al. J Neurosci. (2001) 21(15):5693-702. ( peer-reviewed publication ) |
| Methodology | Quantitative match to experiments |
| Model Implementation | Exact GENESIS implementation |
| Model Validation | Approximates orginal data |
| Notes | This model of sGC is based on the paper by Kuroda S. et al. J Neurosci. (2001) 21(15):5693-702. This models features the activation of sGC by NO, synthesis of cGMP, activity of PKG and PP2A in the synapse. The rates and concentrations have been taken from published literature. |
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