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Molecule Parameter List for CaE1 | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
CaE1 acting as a Molecule in SERCA Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | CaE1 | SERCA
Accession No. : 37 | SERCA
Pathway No. : 187 | 0 | 0.0016667 | No | | 1 Ca bond state of SERCA2a |
CaE1 acting as a Substrate in a reaction in SERCA Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
CaE1 acting as a Product in a reaction in SERCA Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | reac2 | SERCA
Accession No. : 37 | SERCA
Pathway No. : 187 | 50
(uM^-1 s^-1) | 120
(s^-1) | Kd(bf) = 2.4(uM) | - | Substrate
Ca
E1
Product
CaE1
| Kinetic constants for this step had substantial effects on the steady state EP level.
For SERCA2a alone the kf was 200uM
SERCA2a + Wild type Phospholamban kf was reduced to 100uM.
SERCA2a + L37A Phospholamban kf was reduced to 50um as specified by the author ( Mahaney et al. (2000 Mar) Biophys J. 78(3) 1306-23.).
kb in all the cases were maintained at 120/s. |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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