Enter a Search String |
| Special character and space not allowed in the query term. Search string should be at least 2 characters long. |
Molecule Parameter List for EPi | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| EPi participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| SERCA | 37 | Pathway | SERCA |
| All the constants are from: Mahaney JE. et al. Biophys J. (2000) 78(3) 1306-23. New Insights on cardiac Ca-ATPase (expressed in Sf21 cells) regulation by Phosphlamban. | |||
EPi acting as a Molecule in SERCA Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| EPi | SERCA Accession No. : 37 | SERCA Pathway No. : 187 | 0 | 0.0016667 | No | |
| Phosphoenzyme decompostion intermeditate state. | ||||||
EPi acting as a Substrate in a reaction in SERCA Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| reac8 | SERCA Accession No. : 37 | SERCA Pathway No. : 187 | 0.4 (s^-1) | 0 (uM^-1 s^-1) | - | - | Substrate EPi Product E2 pi |
| kf and kb were taken from the literature source
Mahaney et al. (2000 Mar) Biophys J. 78(3) 1306-23. some minor adjustments for step7 and step8 were required to produce a precise simulation of the EP formation and Pi liberation time course as claimed by the author of above literature. | |||||||
EPi acting as a Product in a reaction in SERCA Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| reac7 | SERCA Accession No. : 37 | SERCA Pathway No. : 187 | 0.3 (s^-1) | 0.7 (s^-1) | Keq = 2.3333(uM) | 1sec | Substrate EP Product EPi |
| kf and kb were taken from the literature source Mahaney et al. (2000 Mar) Biophys J. 78(3) 1306-23. Some minor adjustments for steps 7 and 8 were required to prduce a precise simulation of the EP formation and Pi liberation time course | |||||||