DOQCS database

NCBS Home page

Accession List

Pathway List

Authorized Users

Help

News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.

Molecule Parameter List for CaE1_prime

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*CaE1_prime* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	0	0	1	1

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
SERCA	37	Pathway	SERCA
All the constants are from: Mahaney JE. et al. Biophys J. (2000) 78(3) 1306-23. New Insights on cardiac Ca-ATPase (expressed in Sf21 cells) regulation by Phosphlamban.

CaE1_prime acting as a Molecule in SERCA Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
CaE1_prime	SERCA Accession No. : 37	SERCA Pathway No. : 187	0	0.0016667	No
Intermediate form which is result of conformational changes in the enzymes which makes it to bind to 2nd Ca in the next step

CaE1_prime acting as a Substrate in a reaction in SERCA Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
reac4	SERCA Accession No. : 37	SERCA Pathway No. : 187	80 (uM^-1 s^-1)	3.2 (s^-1)	Kd(bf) = 0.04(uM)	-	Substrate Ca CaE1_prime Product Ca2E1_prime
kf and kb were taken from the Table-6 of literature source Mahaney et al. (2000 Mar) Biophys J. 78(3) 1306-23.

CaE1_prime acting as a Product in a reaction in SERCA Network

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
reac3	SERCA Accession No. : 37	SERCA Pathway No. : 187	0.4 (s^-1)	0.4 (s^-1)	Keq = 1(uM)	1.25sec	Substrate CaE1 Product CaE1_prime
kf and kb were taken form Table-6 of literature source ( Mahaney et al. ( 2000 Mar) Biophys J. 78(3) 1306-23.)

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.