 |  CDK2-CyclinA_
activation_
improved |
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Accession information for CDK2-CyclinA_activation_improved (Accession Number 43)
Reaction Scheme
Accession Basic Parameters
| Name | CDK2-CyclinA_activation_improved |
| Accession Type | Pathway |
| Transcriber | Sharat J. Vayttaden, NCBS |
| Developer | May C. Morris, Claire Gondeau, John A. Tainer and Gilles Divita |
| Entry Date (YYYY-MM-DD) | 2003-01-11 00:00:00 |
| Species | Human, Xenopus |
| Tissue | Expressed in E.coli |
| Cell Compartment | Cytosol |
| Source | Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53. ( peer-reviewed publication ) |
| Methodology | Quantitative match to experiments |
| Model Implementation | Exact GENESIS implementation |
| Model Validation | Approximates original data |
| Notes | This version of the model for CDK2/Cyclin A complex activation (expressed in E. coli) is a good match to the data and the simulation matches the graphs Fig.1B and Fig.1B inset. The rate constants though differ from the rate constants in Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53. |
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