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Molecule Parameter List for E1*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

E1* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	1	1	1	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
MAPK_Asthagiri_ no_fb	44	Pathway	MAPK_Asthagiri_no_fb
This is a complex model to examine mechanisms that govern MAPK pathway dynamics in Chinese hamster ovary (CHO) cell lines. This model simulates the results as per the figure 4 of the paper by Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39.

E1* acting as a Molecule in MAPK_Asthagiri_no_fb Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
E1*	MAPK_Asthagiri_ no_fb Accession No. : 44	MAPK_Asthagiri_ no_fb Pathway No. : 192	0	390	No

E1* acting as an Enzyme in MAPK_Asthagiri_no_fb Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
E1* / E2_activ	MAPK_Asthagiri_ no_fb Accession No. : 44	MAPK_Asthagiri_ no_fb Pathway No. : 192	0.0600001	0.1	5	explicit E-S complex	Substrate E2 Product E2*
k2+ =610^8 M-1 min-1, k2- =30 min-1, kcat,2 =6 min-1 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39*

E1* acting as a Substrate for an Enzyme in MAPK_Asthagiri_no_fb Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
P1 / E1*_deactiv	MAPK_Asthagiri_ no_fb Accession No. : 44	MAPK_Asthagiri_ no_fb Pathway No. : 192	0.0600001	0.1	5	explicit E-S complex	Substrate E1* Product E1
kp1+ =610^8 M-1 min-1, kp1- =30 min-1, kpcat,1 =6 min-1 form Asthagiri and Lauffenburger 2001.*

E1* acting as a Product of an Enzyme in MAPK_Asthagiri_no_fb Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
E0* / E1_activ	MAPK_Asthagiri_ no_fb Accession No. : 44	MAPK_Asthagiri_ no_fb Pathway No. : 192	0.0600001	0.1	5	explicit E-S complex	Substrate E1 Product E1*
k1+ =610^8 M-1 min-1, k1- =30 min-1, kcat,1 =6 min-1 and km caluculated to 0.06 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39*

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