| Name | PKA_2003 |
| Accession Type | Network |
| Transcriber | Upinder S. Bhalla, NCBS |
| Developer | Upinder S. Bhalla, NCBS |
| Entry Date (YYYY-MM-DD) | 2003-04-28 00:00:00 |
| Species | Generic mammalian |
| Tissue | Generic |
| Cell Compartment | Cytosol + Cell membrane |
| Source | Bhalla US. (2004) Biophys J. 87(2):733-44. ( peer-reviewed publication ) |
| Methodology | Qualitative |
| Model Implementation | Exact GENESIS implementation |
| Model Validation | Approximates original data |
| Notes | This model consists of receptor-ligand interaction, G-protein activation, Adenylyl cyclase mediated formation of cAMP and activation of PKA in the neuron. Demonstration programs using this model described in Bhalla US. (2004) Biophys J. 87(2):733-44 to generate a dose-response curve using stochastic calculations are available here. |
