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Accession information for PKA_2003 (Accession Number 47)
Reaction Scheme
Accession Basic Parameters
Name | PKA_2003 |
Accession Type | Network |
Transcriber | Upinder S. Bhalla, NCBS |
Developer | Upinder S. Bhalla, NCBS |
Entry Date (YYYY-MM-DD) | 2003-04-28 00:00:00 |
Species | Generic mammalian |
Tissue | Generic |
Cell Compartment | Cytosol + Cell membrane |
Source | Bhalla US. (2004) Biophys J. 87(2):733-44. ( peer-reviewed publication ) |
Methodology | Qualitative |
Model Implementation | Exact GENESIS implementation |
Model Validation | Approximates original data |
Notes | This model consists of receptor-ligand interaction, G-protein activation, Adenylyl cyclase mediated formation of cAMP and activation of PKA in the neuron. Demonstration programs using this model described in Bhalla US. (2004) Biophys J. 87(2):733-44 to generate a dose-response curve using stochastic calculations are available here. |
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