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Molecule Parameter List for PKC-DAG-AA | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| PKC-DAG-AA participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| PKC_2003 | 48 | Pathway | PKC_2003, PKC |
| This model consists of receptor-ligand interaction, G-protein activation, Adenylyl cyclase mediated formation of cAMP and activation of PKA in the neuron. Demonstration programs using this model described in Bhalla US. (2004) Biophys J. 87(2):733-44 to generate a dose-response curve using stochastic calculations are available here. | |||
PKC-DAG-AA acting as a Molecule in PKC_2003 Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| PKC-DAG-AA | PKC_2003 Accession No. : 48 | PKC Pathway No. : 200 | 0 | 1000 | No | |
PKC-DAG-AA acting as a Substrate in a reaction in PKC_2003 Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
A | PKC_2003 Accession No. : 48 | PKC Pathway No. : 200 | 2 (s^-1) | 0.2 (s^-1) | Keq = 0.1(uM) | 0.455sec | Substrate PKC-DAG-AA Product PKC-DAG-AA* |
| Assume slowish too. Schaechter and Benowitz | |||||||
PKC-DAG-AA acting as a Product in a reaction in PKC_2003 Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| PKC-n-DAG-AA | PKC_2003 Accession No. : 48 | PKC Pathway No. : 200 | 0.018 (uM^-1 s^-1) | 2 (s^-1) | Kd(bf) = 111.1111(uM) | - | Substrate AA PKC-DAG Product PKC-DAG-AA |
| Reduced kf to 0.66X to match Shinomura et al data. Initial: kf = 3.3333e-9 New: 2e-9 Newer: 2e-8 kb was 0.2 now 2. | |||||||