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Molecule Parameter List for CheB

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CheB participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
Chemotaxis55Pathway
Chemotaxis 
All parameters used are from the .BCT files for BCT1.1 provided by Matthew Levin from the Computational Biology Group in the Department of Zoology at the University of Cambridge.Bias does not reach 0.7, there is a lag in the response of bias to the 5 sec 1 uM Aspartate pulse as shown by Bray et al. Mol.Biol.Cell (1993) 4(5): 469-482. The June 2003 version of the BCT program is BCT4.3 and is available at the computational biology site of the Zoology department at Cambridge University.

CheB acting as a Molecule in  
Chemotaxis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CheBChemotaxis
Accession No. : 55
Chemotaxis
Pathway No. : 226
1.621.41No
CheB = 1.62e-06 M = 1.62 uM As per Signal 18 in 1SIG_B.BCT provided by Matthew Levin CheB = 1700 molecules per cell As per Enzyme entry 2 in 1ENZ.BCT provided by Cell volume = 1.41e-15 L Bray et al 1993, Mol.Biol.Cell 4: 469-482 Table 1 pp.474

CheB acting as a Substrate in a reaction in  
Chemotaxis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
PhosphotransferChemotaxis
Accession No. : 55
Chemotaxis
Pathway No. : 226
1
(uM^-1 s^-1)
0
(uM^-1 s^-1)
--Substrate
CheAp
CheB

Product
CheA
CheBp
Phosphotransfer from CheAp to CheB Kf = 1 * 10e6 /sec/M = 1 /sec/uM Kb = 0 /sec/M Bray et al 1993, Mol.Biol.Cell 4: 469-482 Table 2 pp.475 Reaction Scheme 9

CheB acting as a Product in a reaction in  
Chemotaxis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
  • Autodephosphoryl
    ation
  • Chemotaxis
    Accession No. : 55
    Chemotaxis
    Pathway No. : 226
    1
    (s^-1)
    0
    (s^-1)
    --Substrate
    CheBp

    Product
    CheB
    Autodephosphorylation of CheBp Kf = 1 /sec Kb = 0 /sec Bray et al 1993, Mol.Biol.Cell 4: 469-482 Table 2 pp.475 Reaction Scheme 10



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