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Molecule Parameter List for TW

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
TW participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
Chemotaxis55Pathway
Chemotaxis 
All parameters used are from the .BCT files for BCT1.1 provided by Matthew Levin from the Computational Biology Group in the Department of Zoology at the University of Cambridge.Bias does not reach 0.7, there is a lag in the response of bias to the 5 sec 1 uM Aspartate pulse as shown by Bray et al. Mol.Biol.Cell (1993) 4(5): 469-482. The June 2003 version of the BCT program is BCT4.3 and is available at the computational biology site of the Zoology department at Cambridge University.

TW acting as a Molecule in  
Chemotaxis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
TWChemotaxis
Accession No. : 55
Chemotaxis
Pathway No. : 226
1.881.41No
Tar-CheW complex TW = 1.88e-06 M = 1.88 uM As per Signal entry 3 in 1SIG_B.BCT provided by Matthew Levin Cell volume = 1.41e-15 L Table 1 pp.474 Bray et al 1993, Mol.Biol.Cell 4: 469-482

TW acting as a Substrate in a reaction in  
Chemotaxis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
Binding[2]Chemotaxis
Accession No. : 55
Chemotaxis
Pathway No. : 226
0.4
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 2.5(uM)-Substrate
CheA
TW

Product
TWA
MYpYpYpYp = 1.51e-09 M = 1.51e-3 uM As per Signal 27 in 1SIG_B.BCT provided by Matthew Levin Cell volume = 1.41e-15 L Table 1 pp.474 Bray et al 1993, Mol.Biol.Cell 4: 469-482

TW acting as a Product in a reaction in  
Chemotaxis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
ComplexingChemotaxis
Accession No. : 55
Chemotaxis
Pathway No. : 226
0.1
(uM^-1 s^-1)
1
(s^-1)
Kd(bf) = 10.0003(uM)-Substrate
CheW
Tar

Product
TW
CheYp = 1.24e-07 M = 1.24e-01 uM As per Signal 22 in 1SIG_B.BCT provided by Matthew Levin CheYp = 1e-08 M = 1e-2 uM As per Set_Yp configuration in 1CONFIG.BCT provided by Matthew Levin Cell volume = 1.41e-15 L Table 1 pp.474 Bray et al 1993, Mol.Biol.Cell 4: 469-482



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