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Molecule Parameter List for CaM_Ca_n-CaNAB

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaM_Ca_n-CaNAB participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1040001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • CaMKII_noPKA_
    model3
  • 62Network
    Shared_Object_CaMKII_noPKA_model3 CaMKII CaM 
    PP1 PP2B PP1_PSD 
    This is the model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 does not include the full PKA regulatory pathway, and instead has a predefined initial amount of active PKA.

    CaM_Ca_n-CaNAB acting as a Molecule in  
    CaMKII_noPKA_model3 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    CaM_Ca_n-CaNAB
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 00.09No

    CaM_Ca_n-CaNAB acting as an Enzyme in  
    CaMKII_noPKA_model3 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1CaM_Ca_n-CaNAB /
    dephosph_inhib1
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 4.970790.344explicit E-S complexSubstrate
    I1*

    Product
    I1
    2CaM_Ca_n-CaNAB /
    dephosph-PP1-I*
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 4.970790.344explicit E-S complexSubstrate
    PP1-I1*

    Product
    PP1-I1
    3CaM_Ca_n-CaNAB /
  • dephosph_
    inhib1_PSD
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 4.970710.344explicit E-S complexSubstrate
    I1*

    Product
    I1
    4CaM_Ca_n-CaNAB /

  • dephosph-PP1-I*_
    PSD
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 4.970710.344explicit E-S complexSubstrate
    PP1-I1*

    Product
    PP1-I1

    CaM_Ca_n-CaNAB acting as a Product in a reaction in  
    CaMKII_noPKA_model3 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • CaMCa4-bind-CaNA
    B
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • PP2B
    Pathway No. : 261
    599.994
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 0.0017(uM)-Substrate
    CaM-Ca4
    CaNAB-Ca4

    Product
    CaM_Ca_n-CaNAB



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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