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Molecule Parameter List for Degraded_TetR

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Degraded_TetR participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
Repressilator68Network
Lambda-cl_gene Lac_gene TetR_gene 
This is a network model termed as Repressilator in which LacI inhibit transcription of tetR which in turn inhibit transcription of Lambda phage. This model simulates the result as per the Fig 1c of the paper : Elowitz MB, Leibler S., Nature. 2000 Jan 20;403(6767):335-8.

Degraded_TetR acting as a Molecule in  
Repressilator Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
Degraded_TetRRepressilator
Accession No. : 68
TetR_gene
Pathway No. : 297
03Yes
Degradation product of TetR protein

Degraded_TetR acting as a Product in a reaction in  
Repressilator Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
  • TetR_
    degradation
  • Repressilator
    Accession No. : 68
    TetR_gene
    Pathway No. : 297
    0.0167
    (s^-1)
    0
    (s^-1)
    --Substrate
    TetR

    Product
    Degraded_TetR
    This reaction denotes the degradation of Tet R the half life of which is ten minutes. t1/2 = 0.693/k where k denotes kf Note: Rates had to be scaled by 1.4 to get appropriate levels Elowitz, M. et al. (2000) Nature 403:335-338



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