 |  RasGTPase |
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Accession information for RasGTPase (Accession Number 71)
Reaction Scheme
Accession Basic Parameters
| Name | RasGTPase |
| Accession Type | Pathway |
| Transcriber | Sharat J. Vayttaden and Pragati Jain, NCBS |
| Developer | Robert A. Phillips, Jackie L. Hunter, John F. Eccleston, and Martin R. Webb |
| Entry Date (YYYY-MM-DD) | 2006-05-12 00:00:00 |
| Species | General Mammalian |
| Tissue | E.coli Expression system |
| Cell Compartment | Cytosol |
| Source | Phillips RA et al Biochemistry. 2003 Apr 8;42(13):3956-65. ( Peer-reviewed publication ) |
| Methodology | Qualitative |
| Model Implementation | Exact GENESIS implementation |
| Model Validation | Approximates original data |
| Notes | Ras is an important regulator of cell growth in all eukaryotic cells. The model represent hydrolysis of active Ras-bound GTP to give inactive Ras-bound GDP catalyzed by GTPase activating proteins i.e NF1. The inactive Ras-bound GDP turns signalling protein off. |
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