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Molecule Parameter List for PKC-DAG-memb*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

PKC-DAG-memb* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	1	0	0	0	0	1

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_PKM	80	Network	Shared_Object_Ajay_Bhalla_2007_PKM,  PKC,  MAPK,   Ras,  CaM,  PKM
This is a non-bistable model of ERKII signaling that also incorporates PKM synthesis triggered by Ca influx. It is a simplified variant of the model of Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80.

PKC-DAG-memb* acting as a Molecule in  Ajay_Bhalla_2007_PKM Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PKC-DAG-memb*	Ajay_Bhalla_ 2007_PKM Accession No. : 80	PKC Pathway No. : 370	0	1.5	No

PKC-DAG-memb* acting as a Summed Molecule in  Ajay_Bhalla_2007_PKM Network

Accession Name	Pathway Name	Target	Input
Ajay_Bhalla_ 2007_PKM Accession No. : 80	Shared_Object_ Ajay_Bhalla_ 2007_PKM Pathway No. : 369	PKC-active	PKC-Ca-memb* PKC-DAG-memb* PKM-zeta

PKC-DAG-memb* acting as a Product in a reaction in  Ajay_Bhalla_2007_PKM Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
PKC-DAG-to-memb	Ajay_Bhalla_ 2007_PKM Accession No. : 80	PKC Pathway No. : 370	1 (s^-1)	0.1 (s^-1)	Keq = 0.1(uM)	0.909sec	Substrate PKC-Ca-DAG Product PKC-DAG-memb*
Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al.