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Molecule Parameter List for BDNF_TrkB2*_clx

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

BDNF_TrkB2*_clx participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	2	0	0	1	1

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
BDNF_Receptor	86	Network	Shared_Object_BDNF_Receptor,  TrKB_mod,  PI3K_mod
BDNF recetor signaling is one of the sub-model in BDNF signaling cascade. BDNF activates TrKB, leading to the stimulation of PI3K and formation of PIP3.

BDNF_TrkB2*_clx acting as a Molecule in  BDNF_Receptor Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
BDNF_TrkB2*_clx	BDNF_Receptor Accession No. : 86	TrKB_mod Pathway No. : 1083	0	999.97	No

BDNF_TrkB2*_clx acting as an Enzyme in  BDNF_Receptor Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	BDNF_TrkB2*_clx / PLC_g_phospho	BDNF_Receptor Accession No. : 86	TrKB_mod Pathway No. : 1083	0.300008	0.5	4	explicit E-S complex	Substrate PLC_g Product PLC_g*
2	BDNF_TrkB2*_clx / Shc_phospho	BDNF_Receptor Accession No. : 86	TrKB_mod Pathway No. : 1083	0.833306	0.3	4	explicit E-S complex	Substrate Shc Product Shc*

BDNF_TrkB2*_clx acting as a Substrate in a reaction in  BDNF_Receptor Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
LR_Internalize	BDNF_Receptor Accession No. : 86	TrKB_mod Pathway No. : 1083	0.01 (s^-1)	0 (uM^-1 s^-1)	-	-	Substrate BDNF_TrkB2*_clx Product Int_BDNF_ TrKB2*_clx Int_BDNF_ TrKB2*_clx

BDNF_TrkB2*_clx acting as a Product in a reaction in  BDNF_Receptor Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
Autophos_TrKB	BDNF_Receptor Accession No. : 86	TrKB_mod Pathway No. : 1083	0.02 (s^-1)	0 (s^-1)	-	-	Substrate BDNF_TrkB2_clx Product BDNF_TrkB2*_clx