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Molecule Parameter List for Shc | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | | BDNF_Receptor | 86 | Network |
Shared_Object_BDNF_Receptor, TrKB_mod, PI3K_mod | | BDNF recetor signaling is one of the sub-model in BDNF signaling cascade. BDNF activates TrKB, leading to the stimulation of PI3K and formation of PIP3. |
Shc acting as a Molecule in BDNF_Receptor Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | Shc | BDNF_Receptor
Accession No. : 86 | PI3K_mod
Pathway No. : 1084 | 0.5 | 999.97 | No |
Shc acting as a Substrate for an Enzyme in BDNF_Receptor Network
Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | BDNF_TrkB2*_clx /
Shc_phospho | BDNF_Receptor
Accession No. : 86 | TrKB_mod
Pathway No. : 1083 | 0.833306 | 0.3 | 4 | explicit E-S complex | Substrate
Shc
Product
Shc*
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Shc acting as a Product in a reaction in BDNF_Receptor Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | Shc*_dephospho | BDNF_Receptor
Accession No. : 86 | PI3K_mod
Pathway No. : 1084 | 0.2
(s^-1) | 0
(s^-1) | - | - | Substrate
Shc*
Product
Shc
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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