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Name Notes Model

Molecule Parameter List for PP2A

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

PP2A participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	3	0	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
S6K	88	Network	Shared_Object_S6K,  mTOR_model,  S6Kinase
Rheb-GTP activates TOR, and along with convergent input from MAPK, leads to S6K activation and formation of the active 40S for translation

PP2A acting as a Molecule in  S6K Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PP2A	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	0.15	1000	No
Protein Phosphatase

PP2A acting as an Enzyme in  S6K Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP2A / dephos_clus_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	8.80009	1	4	explicit E-S complex	Substrate S6K* Product S6K
2	PP2A / dephos_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	8.80009	1	4	explicit E-S complex	Substrate S6K_thr-412 Product S6K*
3	PP2A / dephosp_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	8.80009	1	4	explicit E-S complex	Substrate S6K_thr-252 Product S6K_thr-412