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Molecule Parameter List for TOR_Rheb-GTP_clx | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
| TOR_Rheb-GTP_clx participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | | No. of occurrences | 1 | 0 | 1 | 0 | 0 | 0 | 1 |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | | S6K | 88 | Network |
Shared_Object_S6K, mTOR_model, S6Kinase | | Rheb-GTP activates TOR, and along with convergent input from MAPK, leads to S6K activation and formation of the active 40S for translation |
TOR_Rheb-GTP_clx acting as a Molecule in S6K Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | TOR_Rheb-GTP_clx | S6K
Accession No. : 88 | Shared_Object_
S6K
Pathway No. : 1087 | 0 | 1000 | No |
TOR_Rheb-GTP_clx acting as an Enzyme in S6K Network
Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | TOR_Rheb-GTP_
clx /
S6K_phospho
| S6K
Accession No. : 88 | Shared_Object_
S6K
Pathway No. : 1087 | 0.799974 | 0.06 | 4 | explicit E-S complex | Substrate
S6K*
Product
S6K_thr-412
|
TOR_Rheb-GTP_clx acting as a Product in a reaction in S6K Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | Rheb-GTP_bind_
TORclx | S6K
Accession No. : 88 | mTOR_model
Pathway No. : 1088 | 6
(uM^-1 s^-1) | 3
(s^-1) | Kd(bf) = 0.5(uM) | - | Substrate
Rheb-GTP
TOR-clx
Product
TOR_Rheb-GTP_
clx
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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