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Molecule Parameter List for S6K* | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | | S6K | 88 | Network |
Shared_Object_S6K, mTOR_model, S6Kinase | | Rheb-GTP activates TOR, and along with convergent input from MAPK, leads to S6K activation and formation of the active 40S for translation |
S6K* acting as a Molecule in S6K Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | S6K* | S6K
Accession No. : 88 | S6Kinase
Pathway No. : 1089 | 0 | 1000 | No |
S6K* acting as a Substrate for an Enzyme in S6K Network
| | Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | | 1 | PP2A /
dephos_clus_S6K | S6K
Accession No. : 88 | Shared_Object_
S6K
Pathway No. : 1087 | 8.80009 | 1 | 4 | explicit E-S complex | Substrate
S6K*
Product
S6K
| | 2 | TOR_Rheb-GTP_
clx /
S6K_phospho | S6K
Accession No. : 88 | Shared_Object_
S6K
Pathway No. : 1087 | 0.799974 | 0.06 | 4 | explicit E-S complex | Substrate
S6K*
Product
S6K_thr-412
|
S6K* acting as a Product of an Enzyme in S6K Network
| | Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | | 1 | PP2A /
dephos_S6K | S6K
Accession No. : 88 | Shared_Object_
S6K
Pathway No. : 1087 | 8.80009 | 1 | 4 | explicit E-S complex | Substrate
S6K_thr-412
Product
S6K*
| | 2 | MAPK* /
cluster_
phospho_S6K
| S6K
Accession No. : 88 | Shared_Object_
S6K
Pathway No. : 1087 | 17.2998 | 1 | 4 | explicit E-S complex | Substrate
S6K
Product
S6K*
|
S6K* acting as a Product in a reaction in S6K Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | basal_S6K | S6K
Accession No. : 88 | Shared_Object_
S6K
Pathway No. : 1087 | 0.01
(s^-1) | 0
(s^-1) | - | - | Substrate
S6K
Product
S6K*
|
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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