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Molecule Parameter List for S6K*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

S6K* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	2	2	0	1

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
S6K	88	Network	Shared_Object_S6K,  mTOR_model,  S6Kinase
Rheb-GTP activates TOR, and along with convergent input from MAPK, leads to S6K activation and formation of the active 40S for translation

S6K* acting as a Molecule in  S6K Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
S6K*	S6K Accession No. : 88	S6Kinase Pathway No. : 1089	0	1000	No

S6K* acting as a Substrate for an Enzyme in  S6K Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP2A  / dephos_clus_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	8.80009	1	4	explicit E-S complex	Substrate S6K* Product S6K
2	TOR_Rheb-GTP_ clx  / S6K_phospho	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	0.799974	0.06	4	explicit E-S complex	Substrate S6K* Product S6K_thr-412

S6K* acting as a Product of an Enzyme in  S6K Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP2A  / dephos_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	8.80009	1	4	explicit E-S complex	Substrate S6K_thr-412 Product S6K*
2	MAPK*  / cluster_ phospho_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	17.2998	1	4	explicit E-S complex	Substrate S6K Product S6K*

S6K* acting as a Product in a reaction in  S6K Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
basal_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	0.01 (s^-1)	0 (s^-1)	-	-	Substrate S6K Product S6K*