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Molecule Parameter List for S6K | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S6K participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| S6K | 88 | Network | Shared_Object_S6K, mTOR_model, S6Kinase |
| Rheb-GTP activates TOR, and along with convergent input from MAPK, leads to S6K activation and formation of the active 40S for translation | |||
S6K acting as a Molecule in S6K Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered |
| S6K | S6K Accession No. : 88 | S6Kinase Pathway No. : 1089 | 1.25 | 1000 | No |
S6K acting as a Substrate for an Enzyme in S6K Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents |
| MAPK* / phospho_S6K | S6K Accession No. : 88 | S6K Pathway No. : 1087 | 17.2998 | 1 | 4 | explicit E-S complex | Substrate S6K Product S6K* |
S6K acting as a Product of an Enzyme in S6K Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents |
| PP2A / dephos_clus_S6K | S6K Accession No. : 88 | S6K Pathway No. : 1087 | 8.80009 | 1 | 4 | explicit E-S complex | Substrate S6K* Product S6K |
S6K acting as a Substrate in a reaction in S6K Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| basal_S6K | S6K Accession No. : 88 | S6K Pathway No. : 1087 | 0.01 (s^-1) | 0 (s^-1) | - | - | Substrate S6K Product S6K* |