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Molecule Parameter List for S6K_thr-412

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

S6K_thr-412 participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	1	1	2	2	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
S6K	88	Network	Shared_Object_S6K,  mTOR_model,  S6Kinase
Rheb-GTP activates TOR, and along with convergent input from MAPK, leads to S6K activation and formation of the active 40S for translation

S6K_thr-412 acting as a Molecule in  S6K Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
S6K_thr-412	S6K Accession No. : 88	S6Kinase Pathway No. : 1089	0	1000	No

S6K_thr-412 acting as a Summed Molecule in  S6K Network

Accession Name	Pathway Name	Target	Input
S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	S6K_tot	S6K_thr-412 S6K_thr-252

S6K_thr-412 acting as an Enzyme in  S6K Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
S6K_thr-412 / S6_phos	S6K Accession No. : 88	S6Kinase Pathway No. : 1089	0.250003	0.01	4	explicit E-S complex	Substrate 40S_inact Product 40S

S6K_thr-412 acting as a Substrate for an Enzyme in  S6K Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PDK1  / S6K_phospho	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	10	1	4	explicit E-S complex	Substrate S6K_thr-412 Product S6K_thr-252
2	PP2A  / dephos_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	8.80009	1	4	explicit E-S complex	Substrate S6K_thr-412 Product S6K*

S6K_thr-412 acting as a Product of an Enzyme in  S6K Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP2A  / dephosp_S6K	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	8.80009	1	4	explicit E-S complex	Substrate S6K_thr-252 Product S6K_thr-412
2	TOR_Rheb-GTP_ clx  / S6K_phospho	S6K Accession No. : 88	Shared_Object_ S6K Pathway No. : 1087	0.799974	0.06	4	explicit E-S complex	Substrate S6K* Product S6K_thr-412