 |  MAPK_MKP1_
oscillation |
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Accession information for MAPK_MKP1_oscillation (Accession Number 9)
Reaction Scheme
Accession Basic Parameters
| Name | MAPK_MKP1_oscillation |
| Accession Type | Network |
| Transcriber | Upinder S. Bhalla, NCBS |
| Developer | Upinder S. Bhalla, NCBS |
| Entry Date (YYYY-MM-DD) | 2001-11-08 00:00:00 |
| Species | Generic mammalian |
| Tissue | NIH 3T3 Expression |
| Cell Compartment | Surface - Nucleus |
| Source | Bhalla US, Iyengar R. Chaos (2001) 11(1):221-226. ( peer-reviewed publication ) |
| Methodology | Qualitative |
| Model Implementation | Exact GENESIS implementation |
| Model Validation | Approximates orginal data, Quantitatively predicts new data |
| Notes | This model relates to figure 5 in Bhalla US, Iyengar R. Chaos (2001) 11(1):221-226. It includes the model used for figures 2-4 and also has MKP-1 induction by MAPK activity in the synapse. PP2A is set to 0.16 uM and MKP synthesis is varied from 5x to 40 x basal to get a range of interesting behaviours. |
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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