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Molecule Parameter List for R2C2_dash_cAMP3 | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | mRNA synthesis | 94 | Network | kinetics, compartment_1, compartment_2 | The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway. |
R2C2_dash_cAMP3 acting as a Molecule in mRNA synthesis Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | R2C2_dash_cAMP3 | mRNA synthesis Accession No. : 94 | kinetics Pathway No. : 1112 | 0 | 1000 | No | |
R2C2_dash_cAMP3 acting as a Substrate in a reaction in mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | cAMP_dash_bind_ dash_site_dash_ A2 | mRNA synthesis Accession No. : 94 | kinetics Pathway No. : 1112 | 75 (uM^-1 s^-1) | 32.5 (s^-1) | Kd(bf) = 0.4333(uM) | - | Substrate R2C2_dash_cAMP3 cAMP
Product R2C2_dash_cAMP4
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R2C2_dash_cAMP3 acting as a Product in a reaction in mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | cAMP_dash_bind_ dash_site_dash_ A1 | mRNA synthesis Accession No. : 94 | kinetics Pathway No. : 1112 | 75 (uM^-1 s^-1) | 110 (s^-1) | Kd(bf) = 1.4667(uM) | - | Substrate R2C2_dash_cAMP2 cAMP
Product R2C2_dash_cAMP3
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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