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Molecule Parameter List for R2C2_dash_cAMP3

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
R2C2_dash_cAMP3 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics compartment_1 compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

R2C2_dash_cAMP3 acting as a Molecule in  
mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
R2C2_dash_cAMP3mRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
01000No

R2C2_dash_cAMP3 acting as a Substrate in a reaction in  
mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
  • cAMP_dash_bind_
    dash_site_dash_
    A2
  • mRNA synthesis
    Accession No. : 94
    kinetics
    Pathway No. : 1112
    75
    (uM^-1 s^-1)
    32.5
    (s^-1)
    Kd(bf) = 0.4333(uM)-Substrate
    R2C2_dash_cAMP3
    cAMP

    Product
    R2C2_dash_cAMP4

    R2C2_dash_cAMP3 acting as a Product in a reaction in  
    mRNA synthesis Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • cAMP_dash_bind_
    dash_site_dash_
    A1
  • mRNA synthesis
    Accession No. : 94
    kinetics
    Pathway No. : 1112
    75
    (uM^-1 s^-1)
    110
    (s^-1)
    Kd(bf) = 1.4667(uM)-Substrate
    R2C2_dash_cAMP2
    cAMP

    Product
    R2C2_dash_cAMP3



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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