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Molecule Parameter List for R2_dash_cAMP4

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
R2_dash_cAMP4 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics compartment_1 compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

R2_dash_cAMP4 acting as a Molecule in  
mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
R2_dash_cAMP4mRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
01000No

R2_dash_cAMP4 acting as a Substrate in a reaction in  
mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
dissociationmRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
0.0005
(s^-1)
0.0001
(uM^-1 s^-1)
Kd(cb) = 0.2(uM)-Substrate
R2_dash_cAMP4

Product
R2
cAMP

R2_dash_cAMP4 acting as a Product in a reaction in  
mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
Release_dash_C2mRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
60
(s^-1)
18
(uM^-1 s^-1)
Kd(cb) = 0.3(uM)-Substrate
R2C_dash_cAMP4

Product
PKA_dash_active
R2_dash_cAMP4



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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