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Molecule Parameter List for AC2_star

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
AC2_star participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010110

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics compartment_1 compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

AC2_star acting as a Molecule in  
mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
AC2_starmRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
01000No

AC2_star acting as an Enzyme in  
mRNA synthesis Network
Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
AC2_star /
kenz
mRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
20.114974explicit E-S complexSubstrate
ATP

Product
cAMP

AC2_star acting as a Product of an Enzyme in  
mRNA synthesis Network
Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
PKC_dash_active  /
phosph_dash_AC2
mRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
33.333344explicit E-S complexSubstrate
AC2

Product
AC2_star

AC2_star acting as a Substrate in a reaction in  
mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
  • dephosph_dash_
    AC2
  • mRNA synthesis
    Accession No. : 94
    kinetics
    Pathway No. : 1112
    0.1
    (s^-1)
    0
    (s^-1)
    --Substrate
    AC2_star

    Product
    AC2



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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