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Molecule Parameter List for CRK

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CRK participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000010

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics compartment_1 compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

CRK acting as a Molecule in  
mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CRKmRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
11000No

CRK acting as a Substrate in a reaction in  
mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
C3G_bind_CRKmRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
1
(uM^-1 s^-1)
0.002
(s^-1)
Kd(bf) = 0.002(uM)-Substrate
C3G
CRK

Product
CRK_C3G



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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