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Molecule Parameter List for CRK_C3G

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CRK_C3G participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics compartment_1 compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

CRK_C3G acting as a Molecule in  
mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CRK_C3GmRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
01000No

CRK_C3G acting as a Substrate in a reaction in  
mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
  • CRK_C3G_Cbl_
    star
  • mRNA synthesis
    Accession No. : 94
    kinetics
    Pathway No. : 1112
    1
    (uM^-1 s^-1)
    0.2
    (s^-1)
    Kd(bf) = 0.2(uM)-Substrate
    CRK_C3G
    Cbl_star

    Product
  • CRK_C3G_Cbl_
    star_clx


  • CRK_C3G acting as a Product in a reaction in  
    mRNA synthesis Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    C3G_bind_CRKmRNA synthesis
    Accession No. : 94
    kinetics
    Pathway No. : 1112
    1
    (uM^-1 s^-1)
    0.002
    (s^-1)
    Kd(bf) = 0.002(uM)-Substrate
    C3G
    CRK

    Product
    CRK_C3G



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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