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Molecule Parameter List for CaMKKp

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*CaMKKp* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	1	1	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
mRNA synthesis	94	Network	kinetics, compartment_1, compartment_2
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

CaMKKp acting as a Molecule in mRNA synthesis Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
CaMKKp	mRNA synthesis Accession No. : 94	kinetics Pathway No. : 1112	0	1000	No

CaMKKp acting as a Substrate for an Enzyme in mRNA synthesis Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
PP2A / CaMKKdephosph	mRNA synthesis Accession No. : 94	kinetics Pathway No. : 1112	4.9999	0.7	4	explicit E-S complex	Substrate CaMKKp Product CaMKK_c

CaMKKp acting as a Product of an Enzyme in mRNA synthesis Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
PKA_dash_active / CaMKKphosph	mRNA synthesis Accession No. : 94	kinetics Pathway No. : 1112	4.6999	0.6833	3.99997073156	explicit E-S complex	Substrate CaMKK_CaM_Ca_c Product CaMKKp CaM_dash_Ca4

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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