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Molecule Parameter List for PLC_g

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
PLC_g participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1002001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics compartment_1 compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

PLC_g acting as a Molecule in  
mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
PLC_gmRNA synthesis
Accession No. : 94
kinetics
Pathway No. : 1112
0.11000No

PLC_g acting as a Substrate for an Enzyme in  
mRNA synthesis Network
 Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
1
  • BDNF_TrkB2_
    star_clx
      /
    PLC_g_phospho
  • mRNA synthesis
    Accession No. : 94
    kinetics
    Pathway No. : 1112
    0.30.54explicit E-S complexSubstrate
    PLC_g

    Product
    PLC_g_star
       
    2PLCg_basal  /
    PLC_g_phospho
    mRNA synthesis
    Accession No. : 94
    kinetics
    Pathway No. : 1112
    0.30.54explicit E-S complexSubstrate
    PLC_g

    Product
    PLC_g_star
       

    PLC_g acting as a Product in a reaction in  
    mRNA synthesis Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • PLC_g_p_
    dephospho
  • mRNA synthesis
    Accession No. : 94
    kinetics
    Pathway No. : 1112
    0.07
    (s^-1)
    0
    (s^-1)
    --Substrate
    PLC_g_star

    Product
    PLC_g



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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