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Molecule Parameter List for pTORC1

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
pTORC1 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1001100

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics,  compartment_1,  compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

pTORC1 acting as a Molecule in  mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)		Volume
(fL)		Buffered
pTORC1mRNA synthesis
Accession No. : 94		kinetics
Pathway No. : 1112		01000No

pTORC1 acting as a Substrate for an Enzyme in  mRNA synthesis Network
Enzyme Molecule /
Enzyme Activity		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
  • CaM(Ca)n_dash_
    CaNAB      /
  • CaN_dephos_
    TORC1
    		• mRNA synthesis
    Accession No. : 94    		kinetics
    Pathway No. : 1112    		0.40.14explicit E-S complexSubstrate
    pTORC1

    Product
    TORC1c

    pTORC1 acting as a Product of an Enzyme in      mRNA synthesis Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    SIK2  /
    TORC1_phso_enz    		mRNA synthesis
    Accession No. : 94    		kinetics
    Pathway No. : 1112    		40.44explicit E-S complexSubstrate
    TORC1c

    Product
    pTORC1


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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