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Molecule Parameter List for pMSK1_n

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
pMSK1_n participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1011100

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics,  compartment_1,  compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

pMSK1_n acting as a Molecule in  mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)		Volume
(fL)		Buffered
pMSK1_nmRNA synthesis
Accession No. : 94		compartment_1
Pathway No. : 1113		0370No

pMSK1_n acting as an Enzyme in  mRNA synthesis Network
Enzyme Molecule /
Enzyme Activity		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
pMSK1_n /
  • MSK1_dash_
    phospho
    		• mRNA synthesis
    Accession No. : 94    		compartment_1
    Pathway No. : 1113    		20.14explicit E-S complexSubstrate
    CREB_CRE

    Product
    pCREB_CRE

    pMSK1_n acting as a Substrate for an Enzyme in      mRNA synthesis Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    PP2An  /
    MSK1_dephosp    		mRNA synthesis
    Accession No. : 94    		compartment_1
    Pathway No. : 1113    		8.799914explicit E-S complexSubstrate
    pMSK1_n

    Product
    MSK1_n

    pMSK1_n acting as a Product of an Enzyme in      mRNA synthesis Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    MAPK_star_n  /
    MSK1_phospho    		mRNA synthesis
    Accession No. : 94    		compartment_1
    Pathway No. : 1113    		5.29990.14explicit E-S complexSubstrate
    MSK1_n

    Product
    pMSK1_n


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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