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Molecule Parameter List for CBP

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CBP participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000010

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics compartment_1 compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

CBP acting as a Molecule in  
mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CBPmRNA synthesis
Accession No. : 94
compartment_1
Pathway No. : 1113
0.5370No

CBP acting as a Substrate in a reaction in  
mRNA synthesis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
CBP_binds_pCREBmRNA synthesis
Accession No. : 94
compartment_1
Pathway No. : 1113
0.114
(uM^-1 s^-1)
0.025
(s^-1)
Kd(bf) = 0.2193(uM)-Substrate
CBP
pCREB_CRE

Product
CBP_pCREB_CRE



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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