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Molecule Parameter List for mRNA_clx

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
mRNA_clx participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000210

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics compartment_1 compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

mRNA_clx acting as a Molecule in  
mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
mRNA_clxmRNA synthesis
Accession No. : 94
compartment_1
Pathway No. : 1113
0370No

mRNA_clx acting as a Product of an Enzyme in  
mRNA synthesis Network
 Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
1
  • Basal_
    transcription
      /
  • basal_mRNA_
    synthesis
  • mRNA synthesis
    Accession No. : 94
    compartment_1
    Pathway No. : 1113
    1.08120.054explicit E-S complexSubstrate
    Nucleotides

    Product
    mRNA_clx
       
    2
  • Transcription_
    clx
      /
    mRNA_syn
  • mRNA synthesis
    Accession No. : 94
    compartment_1
    Pathway No. : 1113
    1.080.054explicit E-S complexSubstrate
    Nucleotides

    Product
    mRNA_clx
       

    mRNA_clx acting as a Substrate in a reaction in  
    mRNA synthesis Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    mRNA_elongationmRNA synthesis
    Accession No. : 94
    compartment_1
    Pathway No. : 1113
    1.44
    (s^-1)
    0.0001
    (s^-1)
    Keq = 0.0001(uM)0.694secSubstrate
    mRNA_clx

    Product
    mRNA



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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