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Molecule Parameter List for pCaMKIV_CaM_Ca_nuc

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
pCaMKIV_CaM_Ca_nuc participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1110000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics,  compartment_1,  compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

pCaMKIV_CaM_Ca_nuc acting as a Molecule in  mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)		Volume
(fL)		Buffered
pCaMKIV_CaM_Ca_nucmRNA synthesis
Accession No. : 94		compartment_1
Pathway No. : 1113		0370No

pCaMKIV_CaM_Ca_nuc acting as a Summed Molecule in  mRNA synthesis Network
Accession NamePathway NameTargetInput
mRNA synthesis
Accession No. : 94		compartment_1
Pathway No. : 1113		pCaMKIV_CaM_Ca_nuc
  • pCaMKIV_CaM_Ca_
    n
    Basal_CaMKIV_n

    • pCaMKIV_CaM_Ca_nuc acting as an Enzyme in      mRNA synthesis Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
  • pCaMKIV_CaM_Ca_
    nuc     /
    CREB_phosph
    		• mRNA synthesis
    Accession No. : 94    		compartment_1
    Pathway No. : 1113    		5.50.74explicit E-S complexSubstrate
    CREB_CRE

    Product
    pCREB_CRE


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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