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Molecule Parameter List for Transcription_clx

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Transcription_clx participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mRNA synthesis94Network
kinetics,  compartment_1,  compartment_2 
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

Transcription_clx acting as a Molecule in  mRNA synthesis Network
NameAccession NamePathway NameInitial Conc.
(uM)		Volume
(fL)		Buffered
Transcription_clxmRNA synthesis
Accession No. : 94		compartment_1
Pathway No. : 1113		0370No

Transcription_clx acting as an Enzyme in  mRNA synthesis Network
Enzyme Molecule /
Enzyme Activity		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
  • Transcription_
    clx     /
    mRNA_syn
    		• mRNA synthesis
    Accession No. : 94    		compartment_1
    Pathway No. : 1113    		1.080.054explicit E-S complexSubstrate
    Nucleotides

    Product
    mRNA_clx

    Transcription_clx acting as a Product in a reaction in      mRNA synthesis Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    TORC1_bind_CREBmRNA synthesis
    Accession No. : 94    		compartment_1
    Pathway No. : 1113    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    CBP_pCREB_CRE
    TORC1n

    Product
  • Transcription_
    clx


    • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.