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Molecule Parameter List for R2

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
R2 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Differential syn
    thesis of mRNA
    		• 95Network
    kinetics,  compartment_1,  compartment_2 
    The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

    R2 acting as a Molecule in      Differential synthesis of mRNA Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    R2
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		01000No

    R2 acting as a Substrate in a reaction in      Differential synthesis of mRNA Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    C1_dash_binding
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		799.02
    (uM^-1 s^-1)    		0.186
    (s^-1)    		Kd(bf) = 0.0002(uM)-Substrate
    PKA_dash_active
    R2

    Product
    R2C1
    PMID: 11110787

    R2 acting as a Product in a reaction in      Differential synthesis of mRNA Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    dissociation
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		0.0005
    (s^-1)    		0.0001
    (uM^-1 s^-1)    		Kd(cb) = 0.2(uM)-Substrate
    R2_dash_cAMP4

    Product
    R2
    cAMP


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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