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Molecule Parameter List for CaM.PDE1

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaM.PDE1 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Differential syn
    thesis of mRNA
  • 95Network
    kinetics compartment_1 compartment_2 
    The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

    CaM.PDE1 acting as a Molecule in  
    Differential synthesis of mRNA Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    CaM.PDE1
  • Differential syn
    thesis of mRNA

    Accession No. : 95
  • kinetics
    Pathway No. : 1115
    01000No

    CaM.PDE1 acting as an Enzyme in  
    Differential synthesis of mRNA Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    CaM.PDE1 /
    CaM.PDE1
  • Differential syn
    thesis of mRNA

    Accession No. : 95
  • kinetics
    Pathway No. : 1115
    39.6825104explicit E-S complexSubstrate
    cAMP

    Product
    cAMP

    CaM.PDE1 acting as a Product in a reaction in  
    Differential synthesis of mRNA Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    CaM_bind_PDE1
  • Differential syn
    thesis of mRNA

    Accession No. : 95
  • kinetics
    Pathway No. : 1115
    720
    (uM^-1 s^-1)
    5
    (s^-1)
    Kd(bf) = 0.0069(uM)-Substrate
    CaM_dash_Ca4
    PDE1

    Product
    CaM.PDE1



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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