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Molecule Parameter List for CaMKK_c

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaMKK_c participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000110

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Differential syn
    thesis of mRNA
    		• 95Network
    kinetics,  compartment_1,  compartment_2 
    The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

    CaMKK_c acting as a Molecule in      Differential synthesis of mRNA Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    CaMKK_c
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		0.51000No
    Concentration calculated from PMID: 7883770

    CaMKK_c acting as a Product of an Enzyme in      Differential synthesis of mRNA Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    PP2A  /
    CaMKKdephosph
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		4.99990.74explicit E-S complexSubstrate
    CaMKKp

    Product
    CaMKK_c

    CaMKK_c acting as a Substrate in a reaction in      Differential synthesis of mRNA Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    CaMKKcomplx
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		4.05
    (uM^-1 s^-1)    		0.02
    (s^-1)    		Kd(bf) = 0.0049(uM)-Substrate
    CaMKK_c
    CaM_dash_Ca4

    Product
    CaMKK_CaM_Ca_c
    Kd from PMID: 9705275


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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