Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.

Search in:

ALL Accession Pathway Molecule Enzyme Reaction Connected to

Search for

Match

Anything Exact Word Starting With

By

Name Notes Model

Molecule Parameter List for CaMKK_CaM_Ca_c

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

CaMKK_CaM_Ca_c participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	1	1	0	0	1

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Differential syn thesis of mRNA	95	Network	kinetics,  compartment_1,  compartment_2
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

CaMKK_CaM_Ca_c acting as a Molecule in  Differential synthesis of mRNA Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
CaMKK_CaM_Ca_c	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	0	1000	No

CaMKK_CaM_Ca_c acting as an Enzyme in  Differential synthesis of mRNA Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
CaMKK_CaM_Ca_c / CaMKIVphosph	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	1.3	1.1	4	explicit E-S complex	Substrate CaMKIV_CaM_Ca_c Product pCaMKIV_CaM_Ca_ c

CaMKK_CaM_Ca_c acting as a Substrate for an Enzyme in  Differential synthesis of mRNA Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
PKA_dash_active  / CaMKKphosph	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	4.6999	0.6833	3.99997073156	explicit E-S complex	Substrate CaMKK_CaM_Ca_c Product CaMKKp CaM_dash_Ca4

CaMKK_CaM_Ca_c acting as a Product in a reaction in  Differential synthesis of mRNA Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
CaMKKcomplx	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	4.05 (uM^-1 s^-1)	0.02 (s^-1)	Kd(bf) = 0.0049(uM)	-	Substrate CaMKK_c CaM_dash_Ca4 Product CaMKK_CaM_Ca_c
Kd from PMID: 9705275