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Molecule Parameter List for Shc

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Shc participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1001001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Differential syn
    thesis of mRNA
    		• 95Network
    kinetics,  compartment_1,  compartment_2 
    The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

    Shc acting as a Molecule in      Differential synthesis of mRNA Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    Shc
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		0.51000No

    Shc acting as a Substrate for an Enzyme in      Differential synthesis of mRNA Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
  • BDNF_TrkB2_
    star_clx      /
    Shc_phospho
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		0.83330.34explicit E-S complexSubstrate
    Shc

    Product
    Shc_star

    Shc acting as a Product in a reaction in      Differential synthesis of mRNA Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • Shc_star_
    dephospho
  • Differential syn
    thesis of mRNA
    Accession No. : 95
    		• kinetics
    Pathway No. : 1115    		0.2
    (s^-1)    		0
    (s^-1)    		--Substrate
    Shc_star

    Product
    Shc


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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