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Molecule Parameter List for PLC_g_star

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*PLC_g_star* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	0	2	1	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Differential syn thesis of mRNA	95	Network	kinetics, compartment_1, compartment_2
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

PLC_g_star acting as a Molecule in Differential synthesis of mRNA Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PLC_g_star	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	0	1000	No

PLC_g_star acting as a Product of an Enzyme in Differential synthesis of mRNA Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	BDNF_TrkB2_ star_clx / PLC_g_phospho	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	0.3	0.5	4	explicit E-S complex	Substrate PLC_g Product PLC_g_star

2	PLCg_basal / PLC_g_phospho	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	0.3	0.5	4	explicit E-S complex	Substrate PLC_g Product PLC_g_star

PLC_g_star acting as a Substrate in a reaction in Differential synthesis of mRNA Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
PLC_g_star_ dephospho	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	0.07 (s^-1)	0 (s^-1)	-	-	Substrate PLC_g_star Product PLC_g

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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